Because of these extra roles, drugs that inhibit COX-1 can cause undesirable side effects. COX-2 inhibitors are a kind of NSAID that selectively blocks the COX-2 enzyme and never the COX-1 enzyme. The aim of COX-2 inhibitors is to reduce ache and inflammation without shedding the protection of COX-1 in the gastrointestinal tract. This produces fewer gastrointestinal unintended effects. In 2005, the Commission published a Inexperienced Paper - Selling the Mental Well being of the Inhabitants as a first response to the World Health Organization's Psychological Well being Declaration for Europe. In 2013, a Joint Action Psychological Well being and Well-being was launched with monetary assist from the EU Well being Programme. It's a 3-year initiative that goals to create a framework for action at European stage and builds on the European Pact for Psychological Health and Nicely-being.

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